Intracellular Magnesium-Dependent Modulation of Gap Junction Channels Formed by Neuronal Connexin36
نویسندگان
چکیده
منابع مشابه
Intracellular magnesium-dependent modulation of gap junction channels formed by neuronal connexin36.
Gap junction (GJ) channels composed of Connexin36 (Cx36) are widely expressed in the mammalian CNS and form electrical synapses between neurons. Here we describe a novel modulatory mechanism of Cx36 GJ channels dependent on intracellular free magnesium ([Mg(2+)]i). We examined junctional conductance (gj) and its dependence on transjunctional voltage (Vj) at different [Mg(2+)]i in cultures of He...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2013
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.2825-12.2013